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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FGFR2
All Species:
30.61
Human Site:
S347
Identified Species:
67.33
UniProt:
P21802
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21802
NP_000132.3
821
92025
S347
Y
T
C
L
A
G
N
S
I
G
I
S
F
H
S
Chimpanzee
Pan troglodytes
XP_521622
819
91776
S347
Y
T
C
L
A
G
N
S
I
G
I
S
F
H
S
Rhesus Macaque
Macaca mulatta
XP_001106418
825
91775
S358
Y
T
C
L
A
G
N
S
I
G
I
S
F
H
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P21803
821
91965
S347
Y
T
C
L
A
G
N
S
I
G
I
S
F
H
S
Rat
Rattus norvegicus
Q04589
822
91806
S346
Y
T
C
L
A
G
N
S
I
G
L
S
H
H
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P18461
823
92281
S349
Y
T
C
L
A
G
N
S
I
G
I
S
F
H
T
Frog
Xenopus laevis
Q03364
813
91322
A352
A
W
L
T
V
H
P
A
P
V
N
P
L
E
D
Zebra Danio
Brachydanio rerio
Q8JG38
817
91370
S347
Y
T
C
L
A
G
N
S
I
G
I
S
Y
H
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q09147
1052
117795
G571
Y
T
C
L
A
S
S
G
L
G
R
S
N
S
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10656
1040
118938
S490
Y
A
C
L
S
G
N
S
L
G
M
S
M
A
N
Sea Urchin
Strong. purpuratus
Q26614
972
110463
F506
Y
L
C
V
A
G
N
F
Y
G
M
S
W
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
88.3
N.A.
N.A.
96.9
71.7
N.A.
N.A.
92.8
77.5
77.4
N.A.
29
N.A.
31.6
34.4
Protein Similarity:
100
99.6
90.9
N.A.
N.A.
98.1
83.8
N.A.
N.A.
96.3
87.2
86.5
N.A.
45.1
N.A.
46.5
51.7
P-Site Identity:
100
100
100
N.A.
N.A.
100
86.6
N.A.
N.A.
93.3
0
86.6
N.A.
53.3
N.A.
53.3
46.6
P-Site Similarity:
100
100
100
N.A.
N.A.
100
93.3
N.A.
N.A.
100
6.6
100
N.A.
66.6
N.A.
80
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
82
0
0
10
0
0
0
0
0
10
0
% A
% Cys:
0
0
91
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
19
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
46
0
0
% F
% Gly:
0
0
0
0
0
82
0
10
0
91
0
0
0
0
10
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
10
64
0
% H
% Ile:
0
0
0
0
0
0
0
0
64
0
55
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
10
82
0
0
0
0
19
0
10
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
19
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
82
0
0
0
10
0
10
0
10
% N
% Pro:
0
0
0
0
0
0
10
0
10
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
0
0
0
0
10
10
10
73
0
0
0
91
0
10
55
% S
% Thr:
0
73
0
10
0
0
0
0
0
0
0
0
0
0
19
% T
% Val:
0
0
0
10
10
0
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
91
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _